Anavar (oxandrolone) is not very toxic, not very androgenic, mildly anabolic, and pretty mild on the body´s HPTA (Hypothalamic-Testicular-Pituitary-Axis). Those are its 4 major points, and I´d like to examine each one a bit further; as usual, gym-rumors and internet conjecture has made this steroid the subject of many misconceptions.
Anavar (Oxandrolone) Side Effects
First of all, and this will come as no surprise to many people, Anavar (oxandrolone) is quite mild on your liver. It´s probably the mildest oral steroid available today. Dosages of up to 80mgs/day are easily tolerated by most men, and most side effects often found with other steroids are not common with ´var (1). For this reason, Anavar is frequently the steroid of choice for many top level female bodybuilders and other athletes.
Anavar Dosage
Due to its being a mild steroid in every sense of the word, high amounts of Anavar dosage are needed. It binds reasonably well to the AR, but pretty high doses are still needed and I would never suggest doing less than 20mgs/day. In fact, 20-80mgs are needed to start halting AIDS related wasting(1) and recovering weight for burn victims (2) so that´s the range I´d recommend keeping your dosages in concerning this compound. Personally, I´d use 100mgs/day if I were ever going to try this stuff. Any less than this amount (20-100mgs) would be a waste. For women, however, I think 2.5-10mgs/day would suffice. Virilation is not a concern with this compound, as it is only very mildly androgenic (3). Water retention is also virtually nil with it.
Although Anavar is an oral steroid, and has been alpha-alkylated to survive oral ingestion and the first pass through the liver, it´s still relatively mild in that respect too…, the unique chemical configuration of oxandrolone both confers a resistance to liver metabolism as well as noticable anabolic activity. It would also appear that Anavar appears not to exhibit the serious hepatotoxic effects (jaundice, cholestatic hepatitis, peliosis hepatis, hyperplasias and neoplasms) typically attributed to the C17alpha-alkylated AASs. (17) Anavar has even been used successfully in some studies to heal cutaneous wounds (7), or to improve respiratory function (18). Both of these novel properties could make it a good choice for in-season use for boxers, Mixed Martial Arts competitors, and other such athletes.







