Product Details:
- Brand: Janoshik
- Compound: Tirzepatide
- Dosage Strength: 5 mg per vial
- Form: Injectable (lyophilized powder or reconstituted liquid)
- Purpose: Weight loss, appetite suppression, blood sugar regulation
- Administration Route: Subcutaneous injection
How It Works:
Tirzepatide works by activating both GLP-1 and GIP receptors, two hormones involved in regulating insulin secretion, satiety, and glucose metabolism. This dual agonist action helps:
- Lower blood sugar levels
- Reduce appetite and food cravings
- Slow gastric emptying, increasing feelings of fullness
- Promote weight loss by reducing caloric intake and enhancing insulin sensitivity
Its unique mechanism makes it more effective than GLP-1-only medications like semaglutide in clinical studies.
Who Should Use It?
- Adults with type 2 diabetes looking to improve glycemic control
- Overweight or obese individuals seeking pharmaceutical support for fat loss
- Non-diabetic users using it off-label under professional guidance for weight management
- Not suitable for:
- Type 1 diabetics
- Pregnant or breastfeeding women
- Individuals with a personal/family history of medullary thyroid carcinoma or MEN2
Usage Instructions:
- Starting Dose (common off-label or medical guidance):
- Begin with 2.5 mg once per week, then increase to 5 mg after 4 weeks if well tolerated
- Maintenance Dose: 5–15 mg weekly (5 mg often used for maintenance or initial cycles)
- Injection Site: Subcutaneous (abdomen, thigh, or upper arm)
- Reconstitution (if lyophilized): Mix with sterile water or bacteriostatic water as directed
- Use a sterile syringe, rotate injection sites, and follow aseptic technique
Warnings & Precautions:
- Possible Side Effects:
- Nausea, vomiting, constipation, diarrhea
- Fatigue, dizziness, decreased appetite
- Rare but serious: pancreatitis, gallbladder issues, allergic reactions
- Contraindications:
- History of thyroid cancer (especially medullary thyroid carcinoma)
- Personal or family history of multiple endocrine neoplasia syndrome type 2 (MEN2)
- Drug Interactions: May interact with insulin, sulfonylureas, and other diabetes medications
- Medical supervision recommended, especially if used for non-diabetic weight loss
Storage Instructions:
- Before reconstitution (powder form):
- Store in a cool, dry place at 2–8°C (36–46°F)
- Protect from light
- After reconstitution (liquid):
- Store in refrigerator (2–8°C)
- Use within 14–28 days (depending on diluent and sterility)
- Do not freeze
- Keep out of reach of children and pets
- Discard if discolored, cloudy, or past expiration